Mahmoud N. Mansour

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia

David Cunningham, Dennis E. Danley, Kieran F. Geoghegan et al. · Nature Structural & Molecular Biology · 2007 · 437 citations

Life Sciences, Biochemistry, Molecular Biology +13

Discovery, SAR, and Pharmacokinetics of a Novel 3-Hydroxyquinolin-2(1<i>H</i>)-one Series of Potent<scp>d</scp>-Amino Acid Oxidase (DAAO) Inhibitors

Allen J. Duplantier, Stacey L. Becker, Michael J. Bohanon et al. · Journal of Medicinal Chemistry · 2009 · 110 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Activation of Human Liver Glycogen Phosphorylase by Alteration of the Secondary Structure and Packing of the Catalytic Core

Virginia L. Rath, Mark Ammirati, Peter K. LeMotte et al. · Molecular Cell · 2000 · 98 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Anilinoquinazoline Inhibitors of Fructose 1,6-Bisphosphatase Bind at a Novel Allosteric Site:  Synthesis, In Vitro Characterization, and X-ray Crystallography

Stephen W. Wright, Anthony Carlo, Maynard D. Carty et al. · Journal of Medicinal Chemistry · 2002 · 82 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +17

Theoretical and Experimental Design of Atypical Kinase Inhibitors:  Application to p38 MAP Kinase

Kim F. McClure, Yuriy A. Abramov, Ellen R. Laird et al. · Journal of Medicinal Chemistry · 2005 · 79 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16