Gavin T. Blyth

Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo

Ewa M. Kościuczuk, Diana Saleiro, Barbara Kroczyńska et al. · Blood · 2016 · 46 citations · Full text

Medicine, Cancer Biology, Oncology +14

Identification and targeting of novel CDK9 complexes in acute myeloid leukemia

Elspeth M. Beauchamp, Sameem Abedin, Sara G. Radecki et al. · Blood · 2018 · 41 citations · Full text

Medicine, Molecular Biology, Oncology +12

Pharmacological mTOR targeting enhances the antineoplastic effects of selective PI3Kα inhibition in medulloblastoma

Frank Eckerdt, Jessica Clymer, Jonathan B. Bell et al. · Scientific Reports · 2019 · 32 citations · Full text

Medicine, Oncology, Pharmacology +17

Interferon γ (IFNγ) Signaling via Mechanistic Target of Rapamycin Complex 2 (mTORC2) and Regulatory Effects in the Generation of Type II Interferon Biological Responses

Barbara Kroczyńska, Robert L. Rafidi, Beata Majchrzak-Kita et al. · Journal of Biological Chemistry · 2015 · 29 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Antineoplastic effects of selective CDK9 inhibition with atuveciclib on cancer stem-like cells in triple-negative breast cancer

Daphné Brisard, Frank Eckerdt, Lindsey A. Marsh et al. · Oncotarget · 2018 · 29 citations · Full text

Medicine, Oncology, Pharmacology +17