Jayakanthan Kumarasamy

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Publications

Citations

258

H-Index

Active since

2022

Affiliations

Wave Life Sciences (United States)(Current)

Jayakanthan Kumarasamy is an author at Wave Life Sciences (United States) specializing in chemical modification of oligonucleotides, oligonucleotide chemistry, and oligonucleotide therapeutics.

Publications per year

2022–2024

Publications

Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides

Prashant Monian, Chikdu Shivalila, Genliang Lu et al. · Nature Biotechnology · 2022 · 114 citations

Life Sciences, Biotechnology, Molecular Biology +13

Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS

Kandasamy Pachamuthu, Yuanjing Liu, Vincent Aduda et al. · Nucleic Acids Research · 2022 · 70 citations · Full text

Pharmacy, Neuroscience, Pharmacology +16

Control of backbone chemistry and chirality boost oligonucleotide splice switching activity

Kandasamy Pachamuthu, Graham McClorey, Mamoru Shimizu et al. · Nucleic Acids Research · 2022 · 58 citations · Full text

Pharmacy, Molecular Biology, Pharmacology +15

Rational design of base, sugar and backbone modifications improves ADAR-mediated RNA editing

Genliang Lu, Chikdu Shivalila, Prashant Monian et al. · Nucleic Acids Research · 2024 · 16 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +16

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