Scott C. Brakenridge

Sepsis Pathophysiology, Chronic Critical Illness, and Persistent Inflammation-Immunosuppression and Catabolism Syndrome

Juan C. Mira, Lori F. Gentile, Brittany Mathias et al. · Critical Care Medicine · 2016 · 475 citations · Full text

Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

Kenneth E. Remy, Monty B. Mazer, David A. Striker et al. · JCI Insight · 2020 · 314 citations · Full text

Clinical Immunology, Covid-19-associated Morbidity, Immunodeficiencies +21

Human Myeloid-derived Suppressor Cells are Associated With Chronic Immune Suppression After Severe Sepsis/Septic Shock

Brittany Mathias, Amber L. Delmas, Tezcan Ozrazgat‐Baslanti et al. · Annals of Surgery · 2016 · 257 citations · Full text

Immune Checkpoint Inhibition in Sepsis: A Phase 1b Randomized, Placebo-Controlled, Single Ascending Dose Study of Antiprogrammed Cell Death-Ligand 1 Antibody (BMS-936559)*

Richard S. Hotchkiss, Elizabeth Colston, Sachin Yende et al. · Critical Care Medicine · 2019 · 222 citations · Full text

Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab

Richard S. Hotchkiss, Elizabeth Colston, Sachin Yende et al. · Intensive Care Medicine · 2019 · 177 citations · Full text

Inflammation, Phase 1B, Immunology +6