Eileen Bird

Biphenylsulfonamide Endothelin Receptor Antagonists. 4. Discovery of <i>N</i>-[[2‘-[[(4,5-Dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1‘-biphenyl]- 2-yl]methyl]-<i>N</i>,3,3-trimethylbutanamide (BMS-207940), A Highly Potent and Orally Active ET_A Selective Antagonist

Natesan Murugesan, Zhengxiang Gu, Steven H. Spergel et al. · Journal of Medicinal Chemistry · 2002 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Novel Dual Action AT1 and ETA Receptor Antagonists Reduce Blood Pressure in Experimental Hypertension

Mark C. Kowala, Natesan Murugesan, John E. Tellew et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 52 citations

Medicine, Cardiology, Pharmacology +17

Deficiency in thrombin-activatable fibrinolysis inhibitor (TAFI) protected mice from ferric chloride-induced vena cava thrombosis

Xinkang Wang, Patricia L. Smith, Mei-Yin Hsu et al. · Journal of Thrombosis and Thrombolysis · 2006 · 48 citations

Medicine, Pharmacology, Hemostasis +10

Biphenylsulfonamide Endothelin Antagonists:  Structure−Activity Relationships of a Series of Mono- and Disubstituted Analogues and Pharmacology of the Orally Active Endothelin Antagonist 2‘-Amino-<i>N</i>- (3,4-dimethyl-5-isoxazolyl)-4‘-(2-methylpropyl)[1,1‘-biphenyl]-2-sulfonamide (BMS-187308)

Natesan Murugesan, Zhengxiang Gu, Philip D. Stein et al. · Journal of Medicinal Chemistry · 1998 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Biphenylsulfonamide Endothelin Receptor Antagonists. 2. Discovery of 4‘-Oxazolyl Biphenylsulfonamides as a New Class of Potent, Highly Selective ET_A Antagonists

Natesan Murugesan, Zhengxiang Gu, Philip D. Stein et al. · Journal of Medicinal Chemistry · 2000 · 36 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16