Christian A. Echeverri

A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy

Michelle Becker‐Hapak, Niraj Shrestha, Ethan McClain et al. · Cancer Immunology Research · 2021 · 68 citations · Full text

Immunological Memory, Radiation Oncology, Cancer Immunosurveillance +15

Bifunctional TGF-β trap/IL-15 protein complex elicits potent NK cell and CD8+ T cell immunity against solid tumors

Bai Liu, Xiaoyun Zhu, Lin Kong et al. · Molecular Therapy · 2021 · 37 citations · Full text

Immunotherapeutic HCW9218 augments anti-tumor activity of chemotherapy via NK cell-mediated reduction of therapy-induced senescent cells

Pallavi Chaturvedi, Varghese George, Niraj Shrestha et al. · Molecular Therapy · 2022 · 31 citations · Full text

Immunotherapeutic approach to reduce senescent cells and alleviate senescence‐associated secretory phenotype in mice

Niraj Shrestha, Pallavi Chaturvedi, Xiaoyun Zhu et al. · Aging Cell · 2023 · 25 citations · Full text

A novel interleukin-2-based fusion molecule, HCW9302, differentially promotes regulatory T cell expansion to treat atherosclerosis in mice

Xiaoyun Zhu, Qiongzhen Li, Varghese George et al. · Frontiers in Immunology · 2023 · 10 citations · Full text