Glenn S. Takimoto

The Partial Agonist Activity of Antagonist-Occupied Steroid Receptors Is Controlled by a Novel Hinge Domain-Binding Coactivator L7/SPA and the Corepressors N-CoR or SMRT

Twila A. Jackson, Jennifer K. Richer, David L. Bain et al. · Molecular Endocrinology · 1997 · 464 citations

Life Sciences, Molecular Biology, Pharmacology +17

Progesterone Regulates Transcription of the p21 Cyclindependent Kinase Inhibitor Gene through Sp1 and CBP/p300

Gareth I. Owen, Jennifer K. Richer, Lin Tung et al. · Journal of Biological Chemistry · 1998 · 350 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors.

Lin Tung, Marghny Mohamed, James P. Hoeffler et al. · Molecular Endocrinology · 1993 · 330 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform.

Carol A. Sartorius, Mary Y. Melville, Alicia R. Hovland et al. · Molecular Endocrinology · 1994 · 321 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP.

Carol A. Sartorius, Steve D. Groshong, Louise A. Miller et al. · PubMed · 1994 · 212 citations

Life Sciences, Oncology, Pharmacology +17