Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

Changhan Lee, Lizzia Raffaghello, Sebastian Brandhorst, +10

Science Translational Medicine

Cell DeathMetronomic ChemotherapyYeast CellsGliomaTumor Biology +16

A fully organic retinal prosthesis restores vision in a rat model of degenerative blindness

José Fernando Maya‐Vetencourt, Diego Ghezzi, Maria Rosa Antognazza, +19

Nature Materials

Ganglion CellPhotoreceptor CellRetinaOphthalmologyExperimental Ophthalmology +8

Subretinally injected semiconducting polymer nanoparticles rescue vision in a rat model of retinal dystrophy

José Fernando Maya‐Vetencourt, Giovanni Manfredi, Maurizio Mete, +22

Nature Nanotechnology

NanomedicinePhotoreceptor CellRetinaRetinal DystrophyOphthalmology +6

Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models

Giovanna Bianchi, Roberto Martella, Silvia Ravera, +12

Oncotarget

Chemoprevention StrategyApoptosisCell DeathMetabolic RemodelingWarburg Effect +16

Accelerated Tumor Progression in Mice Lacking the ATP Receptor P2X7

Elena Adinolfi, Marina Capece, Alessia Franceschini, +14

Cancer Research

Atp Receptor P2x7ImmunologyImmunoeditingPathologyImmunotherapeutics +18

Direct inhibition of hexokinase activity by metformin at least partially impairs glucose metabolism and tumor growth in experimental breast cancer

Cecilia Marini, Barbara Salani, Michela Massollo, +20

Cell Cycle

BiochemistryHexokinase ActivityTumor GrowthMedicineDirect Inhibition +12

ATP/P2X7 axis modulates myeloid-derived suppressor cell functions in neuroblastoma microenvironment

Giovanna Bianchi, Marta Vuerich, Patrizia Pellegatti, +7

Cell Death and Disease

LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β

Martina Rossi, Gabriele Bucci, Dario Rizzotto, +12

Nature Communications

Bevacizumab-mediated tumor vasculature remodelling improves tumor infiltration and antitumor efficacy of GD2-CAR T cells in a human neuroblastoma preclinical model

Paola Bocca, Emma Di Carlo, Ignazio Caruana, +10

OncoImmunology

A novel liposomal Clodronate depletes tumor-associated macrophages in primary and metastatic melanoma: Anti-angiogenic and anti-tumor effects

Francesca Piaggio, Vangelis Kondylis, Fabio Pastorino, +15

Journal of Controlled Release

Tumor-associated MacrophagesMedicineNovel Liposomal ClodronateMelanomaImmunology +6