Kira Schützenhofer

Serine-linked PARP1 auto-modification controls PARP inhibitor response

Evgeniia Prokhorova, Florian Zobel, Rebecca Smith et al. · Nature Communications · 2021 · 100 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Cdk5 and GSK3β inhibit fast endophilin-mediated endocytosis

Antonio Ferreira, Alessandra Casamento, Sara Carrillo Roas et al. · Nature Communications · 2021 · 49 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling

Pietro Fontana, Sara C. Buch-Larsen, Osamu Suyari et al. · Nature Communications · 2023 · 26 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Histone ADP-ribosylation promotes resistance to PARP inhibitors by facilitating PARP1 release from DNA lesions

Siham Zentout, Victor Imburchia, Catherine Chapuis et al. · Proceedings of the National Academy of Sciences · 2024 · 17 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist

Esra Balıkçı, Anne-Sophie M. C. Marques, Ludwig G. Bauer et al. · Journal of Medicinal Chemistry · 2024 · 10 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17