Rebecca E. O’Connor

An improved pig reference genome sequence to enable pig genetics and genomics research

Amanda Warr, Nabeel A. Affara, Bronwen Aken et al. · GigaScience · 2020 · 407 citations · Full text

Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19

Britton Boras, Rhys Jones, Brandon J. Anson et al. · Nature Communications · 2021 · 284 citations · Full text

Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1 <i>H</i> -pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia†Coordinates of the PDE10A crystal structures have been deposited in the Protein Data Bank for compound 1 (3HQW), 2 (3HQY), 3 (3HQW) and 9 (3HR1).

Patrick R. Verhoest, Douglas S. Chapin, Michael L. Corman et al. · Journal of Medicinal Chemistry · 2009 · 201 citations · Full text

Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19

Britton Boras, Rhys Jones, Brandon J. Anson et al. · 2020 · 158 citations · Full text

A Comparative Analysis of SARS-CoV-2 Antivirals Characterizes 3CL ^pro Inhibitor PF-00835231 as a Potential New Treatment for COVID-19

Maren de Vries, Adil Mohamed, Rachel A. Prescott et al. · Journal of Virology · 2021 · 139 citations · Full text