Adam Klocperk

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard, Adrian Gervais, Tom Le Voyer et al. · Science Immunology · 2021 · 600 citations · Full text

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

Jérémy Manry, Paul Bastard, Adrian Gervais et al. · Proceedings of the National Academy of Sciences · 2022 · 180 citations · Full text

Ifn Autoantibodies, Immunology, Age Dependent +16

Disharmonic Inflammatory Signatures in COVID-19: Augmented Neutrophils’ but Impaired Monocytes’ and Dendritic Cells’ Responsiveness

Zuzana Paračková, Irena Zentsová, Markéta Bloomfield et al. · Cells · 2020 · 137 citations · Full text

Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome

Jennifer W. Leiding, Tiphanie P. Vogel, Valentine G.J. Santarlas et al. · Journal of Allergy and Clinical Immunology · 2022 · 109 citations · Full text

Stat3 Gain-of-function Syndrome, Monogenic Early-onset Lymphoproliferation, Autoimmune Disease +13

Utility of Ruxolitinib in a Child with Chronic Mucocutaneous Candidiasis Caused by a Novel STAT1 Gain-of-Function Mutation

Markéta Bloomfield, Veronika Kanderová, Zuzana Paračková et al. · Journal of Clinical Immunology · 2018 · 79 citations

Translational Medicine, Pathogenesis, Immunology +5