Dominique Manéchez

Design and Synthesis of Imidazoline Derivatives Active on Glucose Homeostasis in a Rat Model of Type II Diabetes. 1. Synthesis and Biological Activities of <i>N</i>-Benzyl-<i>N</i> ‘-(arylalkyl)-2-(4‘,5‘-dihydro-1‘<i>H</i>-imidazol-2‘-yl)piperazines

Frédéric Rondu, Gae͏̈lle Le Bihan, Xuan Wang et al. · Journal of Medicinal Chemistry · 1997 · 107 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Synthesis of new pyrrolo[1,2-a]quinoxalines: potential non-peptide glucagon receptor antagonists

Jean Guillon, Patrick Dallemagne, Bruno Pfeiffer et al. · European Journal of Medicinal Chemistry · 1998 · 86 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

Design and Synthesis of Imidazoline Derivatives Active on Glucose Homeostasis in a Rat Model of Type II Diabetes. 2. Syntheses and Biological Activities of 1,4-Dialkyl-, 1,4-Dibenzyl, and 1-Benzyl-4-alkyl-2-(4‘,5‘-dihydro-1‘<i>H</i>- imidazol-2‘-yl)piperazines and Isosteric Analogues of Imidazoline

Gae͏̈lle Le Bihan, Frédéric Rondu, Agnès Pelé‐Tounian et al. · Journal of Medicinal Chemistry · 1999 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Effect of S-21663 (PMS 812), an imidazoline derivative, on glucose tolerance and insulin secretion in a rat model of type II diabetes.

Xuan Wang, Frédéric Rondu, Azzdine Lamouri et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 30 citations

Medicine, Endocrinology, Pharmacology +11

Novel thiopyrano[3,2-b] and cycloalkeno[1,2-b]indole derivatives with high inhibitory properties in LTB4 production

Catherine Kuehm‐Caubere, P. Caubère, Brigitte Jamart‐Grégoire et al. · European Journal of Medicinal Chemistry · 1999 · 30 citations

Pharmacy, Chemistry, Pharmacology +10