Real-world data confirm the effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura

Linus A. Völker, Jessica Kaufeld, Wolfgang Miesbach, +39

Blood Advances

Real-world DataImmunologyPharmacotherapyImmunotherapyThrombosis +15

mTOR Regulates Endocytosis and Nutrient Transport in Proximal Tubular Cells

Florian Grahammer, Suresh Krishna Ramakrishnan, Markus M. Rinschen, +15

Journal of the American Society of Nephrology

Cellular PhysiologyRenal FunctionEndocytic PathwayChronic Kidney DiseaseCell Signaling +19

ADAMTS13 and VWF activities guide individualized caplacizumab treatment in patients with aTTP

Linus A. Völker, Jessica Kaufeld, Wolfgang Miesbach, +39

Blood Advances

Impact of first-line use of caplacizumab on treatment outcomes in immune thrombotic thrombocytopenic purpura

Linus A. Völker, Jessica Kaufeld, Gesa Balduin, +61

Journal of Thrombosis and Haemostasis

First-line UseThrombosisThrombopoiesisAutoimmune DiseaseBlood Platelet +6

A fast and simple clearing and swelling protocol for 3D in-situ imaging of the kidney across scales

David Unnersjö‐Jess, Linus Butt, Martin Höhne, +11

Kidney International

Alternate‐day dosing of caplacizumab for immune‐mediated thrombotic thrombocytopenic purpura

Lucas Kühne, Jessica Kaufeld, Linus A. Völker, +12

Journal of Thrombosis and Haemostasis

ThrombosisBlood PlateletHematologyImmunologyAutoimmunity +4

Management of immune thrombotic thrombocytopenic purpura without therapeutic plasma exchange

Lucas Kühne, Paul Knöbl, Kathrin Eller, +22

Blood

Caplacizumab use in immune-mediated thrombotic thrombocytopenic purpura: an international multicentre retrospective Cohort study (The Capla 1000+ project)

Paul Coppo, Michaël Bubenheim, Y. Benhamou, +34

EClinicalMedicine

Repetitive administration of rituximab can achieve and maintain clinical remission in patients with MCD or FSGS

Thomas Osterholt, Polina Todorova, Lucas Kühne, +6

Scientific Reports

Clinical efficacy and safety of switching from eculizumab to ravulizumab in adult patients with aHUS– real-world data

Kristina Schönfelder, Lucas Kühne, Lena Schulte‐Kemna, +6

BMC Nephrology