Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers

Keisuke Kataoka, Yuichi Shiraishi, Yohei Takeda, +41

Nature

Aberrant Pd-l1 ExpressionCancer Cell BiologyPathologyMolecular OncologyCancer Genetics +3

Forward-genetics analysis of sleep in randomly mutagenized mice

Hiromasa Funato, Chika Miyoshi, Tomoyuki Fujiyama, +34

Nature

Knockout MouseSleep DisordersSleepForward-genetics AnalysisSleep Disorder +3

Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition

Akira Honda, Teruo Miyazaki, Junichi Iwamoto, +8

Journal of Lipid Research

Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche

Yu Kitadate, David J. Jörg, Moe Tokue, +20

Cell stem cell

SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells

Moe Tokue, Kanako Ikami, Seiya Mizuno, +15

Stem Cell Reports

SpermatogenesisDifferentiation-promoting Wnt/β-catenin SignalingDevelopmental BiologyGerm CellMedicine +11

Lysophosphatidic acid–induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4

Daisuke Yasuda, Daiki Kobayashi, Noriyuki Akahoshi, +6

Journal of Clinical Investigation

Yap/taz ActivationResponsible Lpa ReceptorsCellular PhysiologyLpa6 Dko RetinasAngiogenesis +18

Simple generation of albino C57BL/6J mice with G291T mutation in the tyrosinase gene by the CRISPR/Cas9 system

Seiya Mizuno, Tra Thi Huong Dinh, Kanako Kato, +8

Mammalian Genome

Knockout MouseCrispr/cas9 SystemGenome SurgeryNatural SciencesGenetics +11

Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation

Channabasavaiah B. Gurumurthy, Aidan R. O’Brien, Rolen M. Quadros, +109

Genome biology

Kinase signalling in excitatory neurons regulates sleep quantity and depth

Staci Jakyong Kim, Noriko Hotta-Hirashima, Fuyuki Asano, +25

Nature

Sleep DisordersSleepSleep DisorderNeurophysiologyReceptor Tyrosine Kinase +8

A mutation in transcription factor MAFB causes Focal Segmental Glomerulosclerosis with Duane Retraction Syndrome

Yoshinori Sato, Hiroyasu Tsukaguchi, Hiroyuki Morita, +22

Kidney International

GlomerulonephritisUrologyDuane Retraction SyndromeFocal Segmental GlomerulosclerosisMendelian Disorder +6