Run‐Zhu Fan

Jolkinolide B targets thioredoxin and glutathione systems to induce ROS-mediated paraptosis and apoptosis in bladder cancer cells

Jun Sang, Wei Li, Hongjuan Diao et al. · Cancer Letters · 2021 · 77 citations

Urology, Signal Transduction, Medicine +10

A natural small molecule alleviates liver fibrosis by targeting apolipoprotein L2

Lu Gan, Qiwei Jiang, Dong Huang et al. · Nature Chemical Biology · 2024 · 37 citations · Full text

Inflammation, Liver Fibrosis, Fibrosis +15

Diterpenoids from Euphorbia royleana reverse P-glycoprotein-mediated multidrug resistance in cancer cells

Sharpkate Shaker, Jun Sang, Xue‐Long Yan et al. · Phytochemistry · 2020 · 36 citations · Full text

Biochemistry, Medicine, Secondary Metabolite +6

Jolkinolide B sensitizes bladder cancer to mTOR inhibitors via dual inhibition of Akt signaling and autophagy

Jun Sang, Lu Gan, Ming-Feng Zou et al. · Cancer Letters · 2021 · 35 citations

Urology, Genitourinary Cancer, Dual Inhibition +6

Design, synthesis and biological evaluation of novel 2,4-diaryl pyrimidine derivatives as selective EGFRL858R/T790M inhibitors

Jianheng Li, Baijiao An, Xianheng Song et al. · European Journal of Medicinal Chemistry · 2020 · 34 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +11