Jolkinolide B targets thioredoxin and glutathione systems to induce ROS-mediated paraptosis and apoptosis in bladder cancer cells

Jun Sang, Wei Li, Hongjuan Diao, +6

Cancer Letters

UrologySignal TransductionMedicineApoptosisCell Death +8

A natural small molecule alleviates liver fibrosis by targeting apolipoprotein L2

Lu Gan, Qiwei Jiang, Dong Huang, +11

Nature Chemical Biology

InflammationLiver FibrosisFibrosisHepatologyBiochemistry +13

Diterpenoids from Euphorbia royleana reverse P-glycoprotein-mediated multidrug resistance in cancer cells

Sharpkate Shaker, Jun Sang, Xue‐Long Yan, +4

Phytochemistry

BiochemistryMedicineSecondary MetabolitePhytopharmacologyAnti-cancer Agent +4

Jolkinolide B sensitizes bladder cancer to mTOR inhibitors via dual inhibition of Akt signaling and autophagy

Jun Sang, Lu Gan, Ming-Feng Zou, +6

Cancer Letters

UrologyGenitourinary CancerDual InhibitionMedicineJolkinolide B +4

Design, synthesis and biological evaluation of novel 2,4-diaryl pyrimidine derivatives as selective EGFRL858R/T790M inhibitors

Jianheng Li, Baijiao An, Xianheng Song, +6

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryBiochemistryMedicineSelective Egfrl858r/t790m Inhibitors +9

Discovery of Highly Potent Daphnane Diterpenoids Uncovers Importin-β1 as a Druggable Vulnerability in Castration-Resistant Prostate Cancer

Jia-Luo Huang, Xue‐Long Yan, Wěi Li, +10

Journal of the American Chemical Society

Ethyl acetate fraction of the root of <i>rubia cordifolia</i> L. inhibits keratinocyte proliferation <i>in vitro</i> and promotes keratinocyte differentiation <i>in vivo</i>: potential application for psoriasis treatment

Zhi‐Xiu Lin, C T, Zhong Zuo, +8

Phytotherapy Research

Melohemsines A-I, melodinus-type alkaloids from Melodinus hemsleyanus

Jian Zhang, Y. DING, Xiao‐Jun Huang, +6

RSC Advances

BiologyMelohemsines A-iBioorganic ChemistryMelodinus-type AlkaloidsNatural Sciences +7

Jatrofolianes A and B: Two Highly Modified Lathyrane Diterpenoids from <i>Jatropha gossypiifolia</i>

Wei Li, Ya-Qi Tang, Jun Sang, +3

Organic Letters

A pair of novel bisindole alkaloid enantiomers from marine fungus <i>Fusarium</i> sp. XBB-9

Sharpkate Shaker, Run‐Zhu Fan, Hou‐Jin Li, +1

Natural Product Research