Discovery of the ergothioneine transporter

Dirk Gründemann, Stephanie Harlfinger, Stefan Gölz, +6

Proceedings of the National Academy of Sciences

Luteinizing hormone reduces the activity of the NPR2 guanylyl cyclase in mouse ovarian follicles, contributing to the cyclic GMP decrease that promotes resumption of meiosis in oocytes

Jerid W. Robinson, Meijia Zhang, Leia C. Shuhaibar, +6

Developmental Biology

OocyteDevelopmental BiologyFertilityCell DivisionOogenesis +13

Dephosphorylation and inactivation of NPR2 guanylyl cyclase in granulosa cells contributes to the LH-induced decrease in cGMP that causes resumption of meiosis in rat oocytes

Jeremy R. Egbert, Leia C. Shuhaibar, Aaron B. Edmund, +8

Development

OocyteGeneticsReproductive BiologyCellular PhysiologyEmbryology +22

TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex

Sonja Dittmer, Zsuzsa Kovács, Shauna H. Yuan, +7

Journal of Cell Science

ApoptosisCell DeathTranscriptional RegulationSignaling PathwayCell Regulation +17

The Carnitine Transporter SLC22A5 Is Not a General Drug Transporter, but It Efficiently Translocates Mildronate

Silke Grigat, Christian Fork, Markus Bach, +4

Drug Metabolism and Disposition

Pharmacological characterization of the first potent and selective antagonist at the cysteinyl leukotriene 2 (CysLT₂) receptor

Frank Wunder, Hanna Tinel, R. Kast, +6

British Journal of Pharmacology

Chemosensory Ca2+ Dynamics Correlate with Diverse Behavioral Phenotypes in Human Sperm

Thomas Veitinger, Jeffrey R. Riffell, Sophie Veitinger, +10

Journal of Biological Chemistry

The Constitutively Active Orphan G-protein-coupled Receptor GPR39 Protects from Cell Death by Increasing Secretion of Pigment Epithelium-derived Growth Factor

Sonja Dittmer, Mert Sahin, Anna Pantlen, +6

Journal of Biological Chemistry

Molecular PhysiologySignal TransductionSignaling PathwayCell RegulationG Protein-coupled Receptor +12

Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction

Christiane Vettel, Marta Lindner, Matthias Dewenter, +20

Circulation Research

Probing the substrate specificity of the ergothioneine transporter with methimazole, hercynine, and organic cations

Silke Grigat, Stephanie Harlfinger, S. Pal, +6

Biochemical Pharmacology

Organic CationsBiochemistryMedicineMembrane TransportSubstrate Specificity +5