Maria Eznarriaga

Developing HDAC4-Selective Protein Degraders To Investigate the Role of HDAC4 in Huntington’s Disease Pathology

Natsuko Macabuag, William Esmieu, Perla Breccia et al. · Journal of Medicinal Chemistry · 2022 · 32 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Optimization of Potent and Selective Ataxia Telangiectasia-Mutated Inhibitors Suitable for a Proof-of-Concept Study in Huntington’s Disease Models

Leticia Toledo‐Sherman, Perla Breccia, Roger Cachope et al. · Journal of Medicinal Chemistry · 2019 · 24 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Convergent activation of Ca ²⁺ permeability in two-pore channel 2 through distinct molecular routes

Ryo� Saito, Qianru Mu, Yu Yuan et al. · Science Signaling · 2023 · 18 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Structure-Based Exploration of Selectivity for ATM Inhibitors in Huntington’s Disease

Amanda Van de Poël, Leticia Toledo‐Sherman, Perla Breccia et al. · Journal of Medicinal Chemistry · 2021 · 13 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17