Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA

Maturada Patchsung, Krittapas Jantarug, Archiraya Pattama, +41

Nature Biomedical Engineering

Viral DiagnosticsCas13-based AssayMedicineDiagnostic TestPathology +7

Protection of tissue physicochemical properties using polyfunctional crosslinkers

Young-Gyun Park, Chang Ho Sohn, Ritchie Chen, +20

Nature Biotechnology

Tissue EngineeringEngineeringCross-linkBiomaterials DesignWound Healing +3

Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery

Michael Segel, Blake Lash, Jingwei Song, +7

Science

Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo

Jonathan Z. Long, Daniel K. Nomura, Robert E. Vann, +8

Proceedings of the National Academy of Sciences

PsychopharmacologyEndocannabinoid CrosstalkPharmacotherapyDrug Discrimination BehaviorSocial Sciences +20

Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of<i>Angptl3</i>

Min Qiu, Zachary Glass, Jinjin Chen, +8

Proceedings of the National Academy of Sciences

In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes

Xin Jin, Sean Simmons, Amy X. Guo, +13

Science

Brain DevelopmentGeneticsRisk GenesDisease Gene IdentificationDevelopmental Neuroscience +20

Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex

Ana Uzquiano, Amanda J. Kedaigle, Martina Pigoni, +16

Cell

Proper AcquisitionCell LineageHuman CellDevelopmental BiologyFate Specification Programs +11

Compact RNA editors with small Cas13 proteins

Soumya Kannan, Han Altae-Tran, Xin Jin, +5

Nature Biotechnology

Compact Rna EditorsNatural SciencesRna Structure PredictionRna BiologyMolecular Biology +4

Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence

Sekyu Choi, Bing Zhang, Sai Ma, +13

Nature

Developmental BiologyCell DivisionCell SignalingCellular SenescenceCell Proliferation +3

Distinct Circuits for the Formation and Retrieval of an Imprinted Olfactory Memory

Xin Jin, Navin Pokala, Cornelia I. Bargmann

Cell

Neurobiological MechanismCognitive ScienceImprinted Olfactory MemoryDistinct CircuitsMemory +7