San‐Qi Zhang

Discovery of potent epidermal growth factor receptor (EGFR) degraders by proteolysis targeting chimera (PROTAC)

Hao Zhang, Hongyi Zhao, Xiao-Xiao Xi et al. · European Journal of Medicinal Chemistry · 2020 · 117 citations

Medicine, Cancer Growth, Cell Growth +5

Discovery of potent small molecule PROTACs targeting mutant EGFR

Hongyi Zhao, Xueyan Yang, Hao Lei et al. · European Journal of Medicinal Chemistry · 2020 · 86 citations

Tumor Biology, Drug Targeting, Mutant Egfr +5

Discovery of Potent PROTACs Targeting EGFR Mutants through the Optimization of Covalent EGFR Ligands

Hongyi Zhao, Haipeng Wang, Yu-Ze Mao et al. · Journal of Medicinal Chemistry · 2022 · 71 citations

A bitter pill for type 2 diabetes? The activation of bitter taste receptor TAS2R38 can stimulate GLP-1 release from enteroendocrine L-cells

Hung T. Pham, Hongxiang Hui, Susan Morvaridi et al. · Biochemical and Biophysical Research Communications · 2016 · 66 citations · Full text

Signal Transduction, Medicine, Physiology +9

Discovery of novel 9-heterocyclyl substituted 9H-purines as L858R/T790M/C797S mutant EGFR tyrosine kinase inhibitors

Hao Lei, Shu Fan, Hao Zhang et al. · European Journal of Medicinal Chemistry · 2019 · 63 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Substituted 9H-purines +9