Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels

Richa Saxena, Benjamin F. Voight, Valeriya Lyssenko, +62

Science

Disease EtiologyGeneticsGenetic EpidemiologyImmunologyHuman Polymorphism +15

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

Hiroyuki Unoki‐Kubota, Atsushi Takahashi, Takahisa Kawaguchi, +26

Nature Genetics

Metabolic SyndromeGenetic DeterminantDiabetes EpidemiologyMedicineGenetics +8

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

Nabila Bouatia‐Naji, Amélie Bonnefond, Christine Cavalcanti-Proença, +37

Nature Genetics

Metabolic SyndromePlasma Glucose LevelsDiabetes EpidemiologyMetabolic DisorderDiabetes Risk +6

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

Yingrui Li, Nicolas Vinckenbosch, Geng Tian, +34

Nature Genetics

Genetic AnalysisAllelic VariantHuman Exomes IdentifiesGenetic DisorderGenetics +6

Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle

Charlotte Ling, Pernille Poulsen, Stina Simonsson, +9

Journal of Clinical Investigation

Muscle FunctionGeneticsDna MethylationHuman PolymorphismGene Characterization +15

Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle

Tina Rönn, Pernille Poulsen, Ola Hansson, +7

Diabetologia

Skeletal MuscleHuman Skeletal MuscleEpigenetic ChangeGeneticsDna Methylation +6

G-allele of Intronic rs10830963 in<i>MTNR1B</i>Confers Increased Risk of Impaired Fasting Glycemia and Type 2 Diabetes Through an Impaired Glucose-Stimulated Insulin Release

Thomas Sparsø, Amélie Bonnefond, Ehm A. Andersson, +25

Diabetes

Common variants in HNF-1 α and risk of type 2 diabetes

Johan Holmkvist, C. Cervin, V. Lyssenko, +8

Diabetologia

Metabolic SyndromeGenetic DeterminantDiabetes EpidemiologyGeneticsDiabetes +10

Common Variants in Maturity-Onset Diabetes of the Young Genes and Future Risk of Type 2 Diabetes

Johan Holmkvist, Peter Almgren, Valeriya Lyssenko, +5

Diabetes

Design of association studies with pooled or un‐pooled next‐generation sequencing data

Su Yeon Kim, Yingrui Li, Yiran Guo, +6

Genetic Epidemiology

BioinformaticsGenome-wide Association StudyNext-generation SequencingGeneticsGenetic Epidemiology +12