Synthesis, structural characterization and biological activity of helicin thiosemicarbazone monohydrate and a copper(II) complex of salicylaldehyde thiosemicarbazone

Maurizio Ferrari, Silvia Capacchi, Giorgio Pelosi, +5

Inorganica Chimica Acta

Biological ActivityBiochemistryNatural SciencesCoordination ComplexBioorganometallic Chemistry +5

Synthesis, spectroscopic characterization and biological properties of new natural aldehydes thiosemicarbazones

Pieralberto Tarasconi, Silvia Capacchi, Giorgio Pelosi, +6

Bioorganic & Medicinal Chemistry

Bioorganic ChemistryBiochemistrySpectroscopic CharacterizationNatural SciencesBiological Properties +5

The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 α (HIF-1α) activity: involvement in myeloma-induced angiogenesis

Simona Colla, Sara Tagliaferri, Francesca Morandi, +18

Blood

Proangiogenic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship to myeloma-induced angiogenesis

Nicola Giuliani, Simona Colla, Mirca Lazzaretti, +17

Blood

Synthesis, characterisation, X-ray structure and biological activity of three new 5-formyluracil thiosemicarbazone complexes

Marisa Belicchi Ferrari, Franco Bisceglie, Giorgio Pelosi, +5

Journal of Inorganic Biochemistry

Biological ActivityInorganic ChemistryEngineeringBiochemistryX-ray Structure +7

Downmodulation of ERK activity inhibits the proliferation and induces the apoptosis of primary acute myelogenous leukemia blasts

Paolo Lunghi, Antonio Tabilio, P Dall'Aglio, +4

Leukemia

Hematological MalignancyErk ActivityReceptor Tyrosine KinaseMalignant Blood DisorderApoptosis +8

Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways

Paolo Lunghi, Nicola Giuliani, Laura Mazzera, +11

Blood

Targeting the Raf/MEK/ERK pathway with small-molecule inhibitors.

James A. McCubrey, Michèle Milella, Agostino Tafuri, +6

PubMed

Growth Factor ReceptorsMolecular PharmacologyTumor BiologyRaf/mek/erk PathwayMedicine +12

Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis

Nicola Giuliani, Paolo Lunghi, Francesca Morandi, +5

Leukemia

Human Myeloma CellsTumor BiologyAngiogenesisSignal TransductionMyeloma-induced Angiogenesis +11

Synthesis, structural characterization and biological activity of p-fluorobenzaldehyde thiosemicarbazones and of a nickel complex

Marisa Belicchi Ferrari, Silvia Capacchi, G. Reffo, +5

Journal of Inorganic Biochemistry

Biological ActivityP-fluorobenzaldehyde ThiosemicarbazonesBiochemistryNatural SciencesNickel Complex +5