Jean Simmermacher

Effect of acute NR2B antagonist treatment on long-term potentiation in the rat hippocampus

John D. Graef, Kimberly Newberry, Amy Newton et al. · Brain Research · 2015 · 46 citations

Life Sciences, Neuroscience, Pharmacology +16

Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction

Sean Kim, Joseph Dinchuk, Monique Anthony et al. · Drug Metabolism and Disposition · 2009 · 45 citations

Medicine, Pharmacokinetics, Pharmacology +17

5,6,7,8-Tetrahydro-1,6-naphthyridine Derivatives as Potent HIV-1-Integrase-Allosteric-Site Inhibitors

Kevin M. Peese, Christopher W. Allard, Timothy P. Connolly et al. · Journal of Medicinal Chemistry · 2019 · 36 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Potent Long-Acting Inhibitors Targeting the HIV-1 Capsid Based on a Versatile Quinazolin-4-one Scaffold

Eric P. Gillis, Michael Bowsher, James H. Cook et al. · Journal of Medicinal Chemistry · 2023 · 24 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Preclinical Characterization of (R)-3-((3S,4S)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate N-Methyl-D-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive Disorder

Linda J. Bristow, Jyoti Gulia, Michael R. Weed et al. · Journal of Pharmacology and Experimental Therapeutics · 2017 · 17 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17