Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution

Alex A. Pollen, Aparna Bhaduri, Madeline G. Andrews, +19

Cell

Developmental BiologyBrain StructureDevelopmental Cognitive NeuroscienceNeuroanatomyCerebral Organoids +5

Characterizing the Major Structural Variant Alleles of the Human Genome

Peter A. Audano, Arvis Sulovari, Tina A. Graves-Lindsay, +13

Cell

Genetic AnalysisAllelic VariantHaplotype DeterminationHuman PhenotypesGenetics +7

Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis

Ian T. Fiddes, Gerrald A. Lodewijk, Meghan Mooring, +24

Cell

Cortical NeurogenesisDevelopmental BiologyNeural Stem CellMolecular NeurobiologyMedicine +4

High-resolution comparative analysis of great ape genomes

Zev Kronenberg, Ian T. Fiddes, David Gordon, +41

Science

Long-read sequence and assembly of segmental duplications

Mitchell R. Vollger, Philip C. Dishuck, Melanie Sorensen, +7

Nature Methods

Long-read SequencingGeneticsLong-read SequenceParallel ProgrammingGenomics +4

Transcriptional fates of human-specific segmental duplications in brain

Max L. Dougherty, Jason G. Underwood, Bradley J. Nelson, +6

Genome Research

Human-specific <i>NOTCH</i> -like genes in a region linked to neurodevelopmental disorders affect cortical neurogenesis

Ian T. Fiddes, Gerrald A. Lodewijk, Meghan Mooring, +24

The birth of a human-specific neural gene by incomplete duplication and gene fusion

Max L. Dougherty, Xander Nuttle, Osnat Penn, +10

Genome biology

An evolutionary driver of interspersed segmental duplications in primates

Stuart Cantsilieris, Susan M. Sunkin, Matthew E. Johnson, +19

Genome biology

Independent expansion, selection, and hypervariability of the <i>TBC1D3</i> gene family in humans

Xavi Guitart, David Porubský, DongAhn Yoo, +9

Genome Research