Genome-wide cell-free DNA fragmentation in patients with cancer

Stephen Cristiano, Alessandro Leal, Jillian Phallen, +33

Nature

Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non–Small Cell Lung Cancer

Valsamo Anagnostou, Kellie N. Smith, Patrick M. Forde, +26

Cancer Discovery

High grade serous ovarian carcinomas originate in the fallopian tube

Sana Intidhar Labidi‐Galy, Eniko Papp, Dorothy Hallberg, +23

Nature Communications

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

Yuchen Jiao, Timothy M. Pawlik, Robert A. Anders, +33

Nature Genetics

Tumor BiologyOncologyHepatologySomatic VariantMedicine +10

Pathologic features of response to neoadjuvant anti-PD-1 in resected non-small-cell lung carcinoma: a proposal for quantitative immune-related pathologic response criteria (irPRC)

Tricia R. Cottrell, Elizabeth D. Thompson, Patrick M. Forde, +27

Annals of Oncology

Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer

Michael J. Topper, Michelle Vaz, Katherine B. Chiappinelli, +15

Cell

Treating Lung CancerReversing Immune EvasionTumor MicroenvironmentEpigenetic ChangeImmunology +6

The genomic landscape of response to EGFR blockade in colorectal cancer

Andrea Bertotti, Eniko Papp, Siân Jones, +32

Nature

OncologyGenomic LandscapeMedicinePathologyColorectal Cancer +7

A Combination of Molecular Markers and Clinical Features Improve the Classification of Pancreatic Cysts

Simeon Springer, Yuxuan Wang, Marco Dal Molin, +64

Gastroenterology

Clinical Features ImprovePancreatic CancerMolecular MarkersPancreatic Fluid CollectionSurgical Pathology +6

Detection and characterization of lung cancer using cell-free DNA fragmentomes

Dimitrios Mathios, Jakob Sidenius Johansen, Stephen Cristiano, +34

Nature Communications

Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer

Nicholas J. Roberts, Alexis L. Norris, Gloria M. Petersen, +42

Cancer Discovery