Engineering Chinese hamster ovary cells to maximize effector function of produced antibodies using FUT8 siRNA

Katsuhiro Mori, Reiko Kuni‐Kamochi, Naoko Yamane‐Ohnuki, +9

Biotechnology and Bioengineering

Establishment of the Anti-Klotho Monoclonal Antibodies and Detection of Klotho Protein in Kidneys

Yukinari Kato, Emi Arakawa, Satoko Kinoshita, +14

Biochemical and Biophysical Research Communications

GlomerulonephritisUrologyRenal FunctionMedicineKidney Failure +8

Comparison of cell lines for stable production of fucose‐negative antibodies with enhanced ADCC

Yutaka Kanda, Naoko Yamane‐Ohnuki, Naoto Sakai, +11

Biotechnology and Bioengineering

Fucose content of monoclonal antibodies can be controlled by culture medium osmolality for high antibody-dependent cellular cytotoxicity

Yoshinobu Konno, Y. Kobayashi, Ken L. Takahashi, +10

Cytotechnology

AllergyMedicineImmunologyAntibody ScreeningMonoclonal Antibodies +5

An anti-ASCT2 monoclonal antibody suppresses gastric cancer growth by inducing oxidative stress and antibody dependent cellular toxicity in preclinical models.

Aya Osanai-Sasakawa, Kenta Hosomi, Yoshiki Sumitomo, +11

PubMed

ImmunologyCancer BiologyTumor BiologyOxidative StressOncology +15

Anti-tumor efficacy evaluation of a novel monoclonal antibody targeting neutral amino acid transporter ASCT2 using patient-derived xenograft mouse models of gastric cancer.

Noriyuki Kasai, Aya Sasakawa, Kenta Hosomi, +9

PubMed

Drug TargetingGastrointestinal OncologyOncogenic AgentMedicineImmunology +12

SUG1, a Component of the 26 S Proteasome, Is an ATPase Stimulated by Specific RNAs

Yasutaka Makino, Kazuya Yamano, Masato Kanemaki, +4

Journal of Biological Chemistry

Structures of the Rat Proteasomal ATPases: Determination of Highly Conserved Structural Motifs and Rules for Their Spacing

Yasutaka Makino, Shingo Yogosawa, Masato Kanemaki, +6

Biochemical and Biophysical Research Communications

Protein FunctionRat ProteasomalCellular EnzymologyProtein AssemblyBiochemistry +10

Human adenosine A3 receptor leads to intracellular Ca2+ mobilization but is insufficient to activate the signaling pathway via phosphoinositide 3-kinase γ in mice

Kazuya Yamano, Miho Inoue, Shigehiro Masaki, +3

Biochemical Pharmacology

Molecular PhysiologySignal TransductionSignaling PathwayMedicinePhysiology +9

Identification of the functional expression of adenosine A3 receptor in pancreas using transgenic mice expressing jellyfish apoaequorin

Kazuya Yamano, Katsuhiro Mori, Ryosuke Nakano, +3

Transgenic Research

Molecular PhysiologySignal TransductionJellyfish ApoaequorinG Protein-coupled ReceptorPhysiology +9