Guangwei He

Design, synthesis and biological evaluation of novel benzoxaborole derivatives as potent PDE4 inhibitors for topical treatment of atopic dermatitis

Zhaoxing Chu, Qinlong Xu, Qihua Zhu et al. · European Journal of Medicinal Chemistry · 2021 · 33 citations · Full text

Medicinal Chemistry, Atopic Dermatitis, Medicine +7

Design, synthesis and biological evaluation of novel imidazo[4,5-c]pyridinecarboxamide derivatives as PARP-1 inhibitors

Qihua Zhu, Xuyan Wang, Zhaoxing Chu et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 32 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Bioorganic Chemistry +11

The neuroprotective effect of a novel agent N2 on rat cerebral ischemia associated with the activation of PI3K/Akt signaling pathway

Jinru Huang, Nandani Darshika Kodithuwakku, Wei He et al. · Neuropharmacology · 2015 · 27 citations

Cell Death, Social Sciences, Neuroprotective Effect +17

Tetramethylpyrazine‑2′O‑sodium ferulate provides neuroprotection against neuroinflammation and brain injury in MCAO/R rats by suppressing TLR-4/NF-κB signaling pathway

Peipei Zhou, Shuzhang Du, Lin Zhou et al. · Pharmacology Biochemistry and Behavior · 2018 · 24 citations

Inflammation, Mcao/r Rats, Tetramethylpyrazine‑2′o‑sodium Ferulate +13

MC-002 exhibits positive effects against platelets aggregation and endothelial dysfunction through thromboxane A 2 inhibition

Weirong Fang, Jie Wei, Dan Han et al. · Thrombosis Research · 2014 · 22 citations

Inflammation, Thrombosis, Platelets Aggregation +13