Laura P. O’Neill

The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote

Dirk Schübeler, David M. MacAlpine, David Scalzo et al. · Genes & Development · 2004 · 799 citations · Full text

Histone Modifications, Epigenetic Change, Genetics +19

The landscape of somatic mutation in normal colorectal epithelial cells

Henry Lee-Six, Sigurgeir Ólafsson, Peter Ellis et al. · Nature · 2019 · 729 citations

Somatic Mutation, Somatic Variant, Somatic Cell Genetics +7

Population dynamics of normal human blood inferred from somatic mutations

Henry Lee-Six, Nina Friesgaard Øbro, Mairi Shepherd et al. · Nature · 2018 · 609 citations · Full text

Allelic Variant, Genetic Testing, Normal Human Blood +9

Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis

Mia Petljak, Ludmil B. Alexandrov, Jonathan Brammeld et al. · Cell · 2019 · 434 citations · Full text

Somatic Variant, Tumor Heterogeneity, Medicine +9

The mutational landscape of human somatic and germline cells

Luiza Moore, Alex Cagan, Tim Coorens et al. · Nature · 2021 · 351 citations

Somatic Variant, Germ Cell, Mutational Landscape +3