In vivo demonstration that α-synuclein oligomers are toxic

Beate Winner, Roberto Jappelli, Samir K. Maji, +16

Proceedings of the National Academy of Sciences

Synaptic TransmissionNeurochemical BiomarkersSynaptic SignalingSocial SciencesNeurobiology Of Disease +20

A large-scale binding and functional map of human RNA-binding proteins

Eric L. Van Nostrand, Peter Freese, Xiaofeng Wang, +35

Nature

Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission

Smruthi Karthikeyan, Joshua I. Levy, Peter De Hoff, +115

Nature

Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9

Ranjan Batra, David A. Nelles, Elaine Pirie, +13

Cell

GeneticsGenetic EngineeringMolecular BiologyMolecular GeneticsGene Editing +5

Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing

Boyko Kakaradov, Janilyn Arsenio, Christella E. Widjaja, +11

Nature Immunology

ChromatinTranscriptional RegulationSystems BiologySingle-cell Rna SequencingEpigenetic Regulation +13

Context-dependent functional compensation between Ythdf m⁶A reader proteins

Lior Lasman, Vladislav Krupalnik, Sergey Viukov, +21

Genes & Development

Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression

Trine Line Hauge Okholm, Shashank Sathe, Samuel S. Park, +12

Genome Medicine

Gene Expression Profiling of Neural Stem Cells and Their Neuronal Progeny Reveals IGF2 as a Regulator of Adult Hippocampal Neurogenesis

Oliver Bracko, Tatjana Singer, Stefan Aigner, +9

Journal of Neuroscience

Adult Stem CellCerebral OrganoidAdult Hippocampal NeurogenesisGene Expression ProfilingSocial Sciences +14

A Large-Scale Binding and Functional Map of Human RNA Binding Proteins

Eric L. Van Nostrand, Peter Freese, Gabriel A. Pratt, +35

EngineeringGeneticsRna LocalizationRna SplicingMolecular Biology +20

Multicellular Self-Assembled Spheroidal Model of the Blood Brain Barrier

Eduard Urich, Christoph Patsch, Stefan Aigner, +3

Scientific Reports

BiofabricationCerebral OrganoidCytoskeletonBiomedical EngineeringCellular Physiology +18