Fitje Losung

Hyrtioreticulins A–E, indole alkaloids inhibiting the ubiquitin-activating enzyme, from the marine sponge Hyrtios reticulatus

Rumi Yamanokuchi, Kumiko Imada, Mitsue Miyazaki et al. · Bioorganic & Medicinal Chemistry · 2012 · 79 citations · Full text

Life Sciences, Biochemistry, Marine Biology +13

Spongiacidin C, a pyrrole alkaloid from the marine sponge Stylissa massa, functions as a USP7 inhibitor

Michitaka Yamaguchi, Mitsue Miyazaki, Matthew P. Kodrasov et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 77 citations · Full text

Natural Sciences, Medicinal Chemistry, Pharmacology +12

Manadosterols A and B, Sulfonated Sterol Dimers Inhibiting the Ubc13–Uev1A Interaction, Isolated from the Marine Sponge <i>Lissodendryx fibrosa</i>

Shuntaro Ushiyama, Hideharu Umaoka, Hikaru Kato et al. · Journal of Natural Products · 2012 · 63 citations

Natural Sciences, Biochemistry, Medicinal Chemistry +15

Siladenoserinols A–L: New Sulfonated Serinol Derivatives from a Tunicate as Inhibitors of p53–Hdm2 Interaction

Yuichi Nakamura, Hikaru Kato, Tadateru Nishikawa et al. · Organic Letters · 2012 · 48 citations

Medicine, Medicinal Chemistry, Pharmacology +7

Manzamine A, a marine-derived alkaloid, inhibits accumulation of cholesterol ester in macrophages and suppresses hyperlipidemia and atherosclerosis in vivo

Keisuke Eguchi, Yukio Fujiwara, A Hayashida et al. · Bioorganic & Medicinal Chemistry · 2013 · 45 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +14