Patrick Page

Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent

Tomonori Aoyama, Yong‐Han Paik, Sumio Watanabe et al. · Hepatology · 2012 · 341 citations

Life Sciences, Molecular Biology, Pharmacology +17

Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo

Joy X. Jiang, Xiangling Chen, Nobuko Serizawa et al. · Free Radical Biology and Medicine · 2012 · 246 citations · Full text

Medicine, Molecular Medicine, Pharmacology +15

First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis

Benoı̂t Laleu, Francesca Gaggini, Mike Orchard et al. · Journal of Medicinal Chemistry · 2010 · 238 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes

Mona Sedeek, Alex Gutsol, Augusto C. Montezano et al. · Clinical Science · 2012 · 155 citations

Medicine, Nephrology, Pharmacology +16

The Nox4 Inhibitor GKT137831 Attenuates Hypoxia-Induced Pulmonary Vascular Cell Proliferation

David E. Green, Tamara C. Murphy, Bum‐Yong Kang et al. · American Journal of Respiratory Cell and Molecular Biology · 2012 · 145 citations · Full text

Medicine, Pharmacology, Physiology +17