Libbey S. O′Farrell

LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept

Tamer Coşkun, Shweta Urva, William C. Roell et al. · Cell Metabolism · 2022 · 246 citations · Full text

Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation

Yongguo Li, Katharina Schnabl, Sarah-Madeleine Gabler et al. · Cell · 2018 · 222 citations

Energy Homeostasis, Protein Secretion, Developmental Biology +8

GIPR agonism mediates weight-independent insulin sensitization by tirzepatide in obese mice

Ricardo J. Samms, Michael E. Christe, Kyla Collins et al. · Journal of Clinical Investigation · 2021 · 204 citations · Full text

The novel dual glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1 ( <scp>GLP</scp> ‐1) receptor agonist tirzepatide transiently delays gastric emptying similarly to selective <scp>long‐acting GLP</scp> ‐1 receptor agonists

Shweta Urva, Tamer Coşkun, Corina Loghin et al. · Diabetes Obesity and Metabolism · 2020 · 116 citations · Full text

Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor

Ajit Regmi, Eitaro Aihara, Michael E. Christe et al. · Cell Metabolism · 2024 · 82 citations · Full text

Long-acting Gipr Agonist, Insulin Signaling, Gastrointestinal Peptide Hormone +17