Emmanuel Onua

Antagonists of the EP₃ Receptor for Prostaglandin E₂ Are Novel Antiplatelet Agents That Do Not Prolong Bleeding

Jasbir Singh, Wayne E. Zeller, Nian Zhou et al. · ACS Chemical Biology · 2009 · 69 citations

Medicine, Cardiology, Pharmacology +17

Discovery of 4-[(2<i>S</i>)-2-{[4-(4-Chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic Acid (DG-051) as a Novel Leukotriene A4 Hydrolase Inhibitor of Leukotriene B4 Biosynthesis

Vincent Sandanayaka, B. Mamat, Rama K. Mishra et al. · Journal of Medicinal Chemistry · 2009 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

3,4-Disubstituted indole acylsulfonamides: A novel series of potent and selective human EP3 receptor antagonists

Nian Zhou, Wayne E. Zeller, Michael Krohn et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 42 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Structure−Activity Relationship Studies Leading to the Identification of (2<i>E</i>)-3-[l-[(2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-l<i>H</i>-indol-7-yl]-<i>N</i>-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide (DG-041), a Potent and Selective Prostanoid EP3 Receptor Antagonist, as a Novel Antiplatelet Agent That Does Not Prolong Bleeding

Jasbir Singh, Wayne E. Zeller, Nian Zhou et al. · Journal of Medicinal Chemistry · 2009 · 41 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Oral toxicity and pharmacokinetic studies of SHetA2, a new chemopreventive agent, in rats and dogs

Kasim K. Kabirov, Izet M. Kapetanović, Doris M. Benbrook et al. · Drug and Chemical Toxicology · 2012 · 40 citations

Pharmacy, Pharmacokinetics, Pharmacology +13