m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways

Huabing Li, Jiyu Tong, Shu Zhu, +15

Nature

Il-7/stat5/socs PathwaysCytokineT Cell HomeostasisAutoimmune DiseaseImmune Cell Development +8

Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis

Roni Nowarski, Ruaidhrí Jackson, Nicola Gagliani, +8

Cell

InflammationMucosal ImmunologyImmunologyUlcerative ColitisMedicine

Circuit Design Features of a Stable Two-Cell System

Xu Zhou, Ruth A. Franklin, Miri Adler, +7

Cell

Electrical EngineeringEngineeringCircuit SystemCircuit DesignBioelectronics +5

β-Hydroxybutyrate suppresses colorectal cancer

Oxana Dmitrieva-Posocco, Andrea C. Wong, Patrick Lundgren, +33

Nature

Tumor BiologyChemoprevention StrategyGastrointestinal OncologyMedicinePharmacology +3

The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan

Jonathan J. Kotzin, Sean P. Spencer, Sam J. McCright, +21

Nature

Developmental BiologyLongevityRna BiologyCell DeathLong Non-coding Rna +5

The translation of non-canonical open reading frames controls mucosal immunity

Ruaidhrí Jackson, Lina Kroehling, Alexandra Khitun, +14

Nature

InflammationTranslational MedicineMucosal ImmunologyInnate Immune SystemImmunology +8

T Cell Factor 1 Is Required for Group 2 Innate Lymphoid Cell Generation

Qi Yang, Laurel A. Monticelli, Steven A. Saenz, +12

Immunity

Group 2Autoimmune DiseaseAdaptive Immune SystemT-regulatory CellImmunology +9

Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function

Will Bailis, Justin A. Shyer, Jun Zhao, +12

Nature

Systems BiologyMitochondrial FunctionMitochondrial DynamicDistinct ModesMetabolism +3

Skin-resident innate lymphoid cells converge on a pathogenic effector state

Piotr Bielecki, Samantha J. Riesenfeld, Jan-Christian Hütter, +29

Nature

InflammationAutoimmune DiseaseInnate Immune SystemImmunologyImmune Regulation +7

Long-range enhancer activity determines <i>Myc</i> sensitivity to Notch inhibitors in T cell leukemia

Yumi Yashiro–Ohtani, Hongfang Wang, Chongzhi Zang, +17

Proceedings of the National Academy of Sciences