Joerg Trappe

Characterization of the Novel and Specific PI3Kα Inhibitor NVP-BYL719 and Development of the Patient Stratification Strategy for Clinical Trials

Christine Fritsch, Alan Huang, Christian Chatenay‐Rivauday et al. · Molecular Cancer Therapeutics · 2014 · 496 citations

Medicine, Oncology, Pharmacology +16

Targeting Plasmodium PI(4)K to eliminate malaria

Case W. McNamara, Chek Shik Lim, Siau Hoi Lim et al. · Nature · 2013 · 426 citations · Full text

Pharmacy, Infectious Diseases, Pharmacology +12

Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805

Fabienne Baffert, Catherine H. Régnier, Alain De Pover et al. · Molecular Cancer Therapeutics · 2010 · 120 citations

Medicine, Molecular Biology, Pharmacology +13

Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers

Pablo D. García, John L. Langowski, Yingyun Wang et al. · Clinical Cancer Research · 2014 · 111 citations · Full text

Medicine, Oncology, Pharmacology +17

Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor

Alexei S. Karpov, Payman Amiri, Cornelia Bellamacina et al. · ACS Medicinal Chemistry Letters · 2015 · 109 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16