Kithsiri Herath

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

Jun Wang, S.M. Soisson, Katherine Young et al. · Nature · 2006 · 809 citations

Antibiotics, Medicine, Pharmacotherapy +11

Discovery of platencin, a dual FabF and FabH inhibitor with <i>in vivo</i> antibiotic properties

Jun Wang, Srinivas Kodali, Sang Ho Lee et al. · Proceedings of the National Academy of Sciences · 2007 · 380 citations · Full text

Bioorganic Chemistry, Engineering, Antibiotic Adjuvant +20

Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy

Sheo B. Singh, Hiranthi Jayasuriya, John G. Ondeyka et al. · Journal of the American Chemical Society · 2006 · 230 citations

Bioorganic Chemistry, Antimicrobial Chemotherapy, Chemical Biology +20

Discovery of FabH/FabF Inhibitors from Natural Products

Katherine Young, Hiranthi Jayasuriya, John G. Ondeyka et al. · Antimicrobial Agents and Chemotherapy · 2006 · 199 citations · Full text

Fabh/fabf Inhibitors, Engineering, Antisense Rna +19

Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad‐Spectrum Antibiotic Activity

Hiranthi Jayasuriya, Kithsiri Herath, Chaowei Zhang et al. · Angewandte Chemie International Edition · 2007 · 196 citations

Pharmacotherapy, Antimicrobial Chemotherapy, Chemical Biology +19