Ko-ichi Ichihashi

Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection

Toshiro Hirai, Tomoaki Yoshikawa, Hiromi Nabeshi et al. · Particle and Fibre Toxicology · 2012 · 87 citations · Full text

Life Sciences, Dermatology, Immunology +17

Intranasal exposure to amorphous nanosilica particles could activate intrinsic coagulation cascade and platelets in mice

Tokuyuki Yoshida, Yasuo Yoshioka, Saeko Tochigi et al. · Particle and Fibre Toxicology · 2013 · 68 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

Metal nanoparticles in the presence of lipopolysaccharides trigger the onset of metal allergy in mice

Toshiro Hirai, Yasuo Yoshioka, Natsumi Izumi et al. · Nature Nanotechnology · 2016 · 68 citations

Life Sciences, Immunology, Allergy +12

Amorphous silica nanoparticles enhance cross-presentation in murine dendritic cells

Toshiro Hirai, Yasuo Yoshioka, Hideki Takahashi et al. · Biochemical and Biophysical Research Communications · 2012 · 46 citations

Life Sciences, Immunology, Materials Science +14

Cutaneous exposure to agglomerates of silica nanoparticles and allergen results in IgE-biased immune response and increased sensitivity to anaphylaxis in mice

Toshiro Hirai, Yasuo Yoshioka, Hideki Takahashi et al. · Particle and Fibre Toxicology · 2015 · 26 citations · Full text

Life Sciences, Dermatology, Immunology +17