William O’Gorman

Peripheral T cell expansion predicts tumour infiltration and clinical response

Thomas D. Wu, Shravan Madireddi, Patrícia E. de Almeida et al. · Nature · 2020 · 795 citations

Life Sciences, Immunology, Oncology +16

Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes

Maha K. Rahim, Trine Line Hauge Okholm, Kyle B. Jones et al. · Cell · 2023 · 412 citations · Full text

Life Sciences, Immunology, Oncology +17

Intratumoral plasma cells predict outcomes to PD-L1 blockade in non-small cell lung cancer

Namrata S. Patil, Barzin Y. Nabet, Sören Müller et al. · Cancer Cell · 2022 · 403 citations

Medicine, Immunology, Oncology +16

Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses

Karl L. Banta, Xiaozheng Xu, Avantika S. Chitre et al. · Immunity · 2022 · 347 citations · Full text

Medicine, Immunology, Pharmacology +17

U1 snRNA associates with TFIIH and regulates transcriptional initiation

Kon Yew Kwek, Shona Murphy, André Furger et al. · Nature Structural Biology · 2002 · 256 citations

Life Sciences, Genetics, Molecular Biology +14