Wenpei Shan

Piperlonguminine and Piperine Analogues as TrxR Inhibitors that Promote ROS and Autophagy and Regulate p38 and Akt/mTOR Signaling

Peng Zhu, Jianqiang Qian, Zhongyuan Xu et al. · Journal of Natural Products · 2020 · 44 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

A Derivative of Piperlongumine and Ligustrazine as a Potential Thioredoxin Reductase Inhibitor in Drug-Resistant Hepatocellular Carcinoma

Jianqiang Qian, Zhongyuan Xu, Peng Zhu et al. · Journal of Natural Products · 2021 · 26 citations

Medicine, Medicinal Chemistry, Pharmacology +16

GSH/ROS Dual-Responsive Supramolecular Nanoparticles Based on Pillar[6]arene and Betulinic Acid Prodrug for Chemo–Chemodynamic Combination Therapy

Peng Zhu, Weidan Luo, Jianqiang Qian et al. · Molecules · 2021 · 15 citations · Full text

Medicine, Oncology, Pharmacology +17

Novel Phenylmethylenecyclohexenone Derivatives as Potent TrxR Inhibitors Display High Antiproliferative Activity and Induce ROS, Apoptosis, and DNA Damage

Xiaomei Wang, Jianqiang Qian, Peng Zhu et al. · ChemMedChem · 2020 · 14 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Novel Hybrid CHC from β-carboline and N-Hydroxyacrylamide Overcomes Drug-Resistant Hepatocellular Carcinoma by Promoting Apoptosis, DNA Damage, and Cell Cycle Arrest

Jiefei Miao, Chi Meng, Hongmei Wu et al. · Frontiers in Pharmacology · 2021 · 13 citations · Full text

Medicine, Oncology, Pharmacology +17