Tsuyoshi Notake

Survival pathway of cholangiocarcinoma via AKT/mTOR signaling to escape RAF/MEK/ERK pathway inhibition by sorafenib

Kenta Yokoi, Akira Kobayashi, Hiroaki Motoyama et al. · Oncology Reports · 2017 · 39 citations · Full text

Medicine, Oncology, Pharmacology +17

Safety and Oncological Benefit of Hepatopancreatoduodenectomy for Advanced Extrahepatic Cholangiocarcinoma with Horizontal Tumor Spread: Shinshu University Experience

Akira Shimizu, Hiroaki Motoyama, Kôji Kubota et al. · Annals of Surgical Oncology · 2020 · 32 citations

Medicine, Oncology, Surgery +13

Impact of advanced age on the short- and long-term outcomes in patients undergoing hepatectomy for hepatocellular carcinoma: a single-center analysis over a 20-year period

Hiroaki Motoyama, Akira Kobayashi, Takahide Yokoyama et al. · The American Journal of Surgery · 2014 · 31 citations

Medicine, Oncology, Surgery +14

Assessment of treatment outcomes based on tumor marker trends in patients with recurrent hepatocellular carcinoma undergoing trans-catheter arterial chemo-embolization

Takuma Arai, Akira Kobayashi, Ayumi Ohya et al. · International Journal of Clinical Oncology · 2013 · 30 citations

Medicine, Oncology, Surgery +14

Increased mitochondria are responsible for the acquisition of gemcitabine resistance in pancreatic cancer cell lines

Hitoshi Masuo, Kôji Kubota, Akira Shimizu et al. · Cancer Science · 2023 · 28 citations · Full text

Life Sciences, Cell Biology, Oncology +17