Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes

Tongyan Liu, Changxiang Shi, Run Gao, +8

Clinical Science

Glucose ProductionMetabolic RemodelingInsulin SignalingOxidative StressMetabolic Syndrome +18

FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity

Xiao‐Qing Xiong, Dan Chen, Hai‐Jian Sun, +10

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

ObesityMetabolic SyndromeFndc5 OverexpressionBiochemistryPhysiology +9

NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension

Hai‐Jian Sun, Xingsheng Ren, Xiao‐Qing Xiong, +9

Cell Death and Disease

InflammationNlrp3 GeneSignal TransductionInflammatory DiseaseVsmc Phenotype Switching +11

FNDC5 attenuates adipose tissue inflammation and insulin resistance via AMPK-mediated macrophage polarization in obesity

Xiao‐Qing Xiong, Zhi Geng, Bing Zhou, +9

Metabolism

Insulin ResistanceMetabolic SyndromeObesityInflammationSignal Transduction +12

The Small Hydrophobic Protein of the Human Respiratory Syncytial Virus Forms Pentameric Ion Channels

Siok Wan Gan, Edward Tan, Xin Lin, +9

Journal of Biological Chemistry

FNDC5 Alleviates Hepatosteatosis by Restoring AMPK/mTOR-Mediated Autophagy, Fatty Acid Oxidation, and Lipogenesis in Mice

Tongyan Liu, Xiao‐Qing Xiong, Xingsheng Ren, +11

Diabetes

β-aminoisobutyric acid attenuates hepatic endoplasmic reticulum stress and glucose/lipid metabolic disturbance in mice with type 2 diabetes

Changxiang Shi, Mingxia Zhao, Xiaodong Shu, +7

Scientific Reports

MiR155‐5p in adventitial fibroblasts‐derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin‐converting enzyme expression

Xingsheng Ren, Ying Tong, Yun Qiu, +13

Journal of Extracellular Vesicles

HypertensionVascular AceExtracellular MicrovesiclesVsmc ProliferationBiomedical Engineering +16

Salusin-β Promotes Vascular Smooth Muscle Cell Migration and Intimal Hyperplasia After Vascular Injury <i>via</i> ROS/NFκB/MMP-9 Pathway

Hai‐Jian Sun, Mingxia Zhao, Xingsheng Ren, +6

Antioxidants and Redox Signaling

Exosome-Mediated Transfer of ACE (Angiotensin-Converting Enzyme) From Adventitial Fibroblasts of Spontaneously Hypertensive Rats Promotes Vascular Smooth Muscle Cell Migration

Ying Tong, Chao Ye, Xingsheng Ren, +8

Hypertension