Patterns and rates of exonic de novo mutations in autism spectrum disorders

Benjamin M. Neale, Yan Kou, Li Liu, +56

Nature

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Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells

Zharko Daniloski, Tristan X. Jordan, Hans‐Hermann Wessels, +14

Cell

Sars-cov-2 InfectionHuman CellsViral PathogenesisImmunologyVirology +6

Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

Naomi Kouri, Owen A. Ross, Beth A. Dombroski, +49

Nature Communications

Massively parallel discovery of human-specific substitutions that alter enhancer activity

Severin Uebbing, Jake Gockley, Steven K. Reilly, +6

Proceedings of the National Academy of Sciences

Profiling the genetic determinants of chromatin accessibility with scalable single-cell CRISPR screens

Noa Liscovitch‐Brauer, Antonino Montalbano, Jiale Deng, +10

Nature Biotechnology

ChromatinChromatin RemodelingMedicineGeneticsGenetic Engineering +9

Antisense-mediated Exon Skipping Decreases Tau Protein Expression: A Potential Therapy For Tauopathies

Reeteka Sud, Evan Geller, Gerard D. Schellenberg

Molecular Therapy — Nucleic Acids

Neurodegenerative DiseasesAlzheimer's DiseaseAutoimmune DiseaseAllergyProtein Tau +11

A Statistical Framework for Mapping Risk Genes from De Novo Mutations in Whole-Genome-Sequencing Studies

Yuwen Liu, Yanyu Liang, A. Ercüment Çiçek, +17

The American Journal of Human Genetics

Statistical FrameworkNext-generation SequencingGeneticsRisk GenesGenetic Epidemiology +9

Massively parallel disruption of enhancers active in human neural stem cells

Evan Geller, Mark Noble, Matheo Morales, +5

Cell Reports

Septic Arthritis in a Patient With Juvenile Rheumatoid Arthritis

Scott T. Sauer, Eric Farrell, Evan Geller, +1

Clinical Orthopaedics and Related Research

Rheumatoid DisorderRheumatologyJoint SepsisAutoimmune DiseaseAllergy +12