Frank Miedema

Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population

Hanneke Schuitemaker, M. Koot, Neeltje A. Kootstra et al. · Journal of Virology · 1992 · 1K citations · Full text

Primary Immunodeficiency, Biological Phenotype, Hiv-1 Populations +15

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

Stephen A. Migueles, Alisha C. Laborico, W. Lesley Shupert et al. · Nature Immunology · 2002 · 979 citations

Autoimmune Disease, Human Retrovirus, T-regulatory Cell +9

Programmed Death of T Cells in HIV-1 Infection

Linde Meyaard, Sigrid A. Otto, Richard R. Jonker et al. · Science · 1992 · 918 citations

Programmed Death, Apoptosis, Immunology +16

Persistent immune activation in HIV-1 infection is associated with progression to AIDS

Mette D. Hazenberg, Sigrid A. Otto, Birgit HB van Benthem et al. · AIDS · 2003 · 774 citations

Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule

Ron A. M. Fouchier, M Groenink, Neeltje A. Kootstra et al. · Journal of Virology · 1992 · 768 citations · Full text

Viral Replication, Immunology, Molecular Biology +21