The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma

Parvez Vora, Chitra Venugopal, Sabra K. Salim, +25

Cell stem cell

Neuro-oncologyRational DevelopmentImmunologyImmune Checkpoint InhibitorImmunotherapeutics +4

Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma

William D. Gwynne, Yujin Suk, Stefan Custers, +23

Cancer Cell

OncologyCancer-selective Metabolic VulnerabilitiesOncogenic AgentMedicinePathology +3

An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex

Michal Hammel, Yaping Yu, Sarvan Kumar Radhakrishnan, +9

Journal of Biological Chemistry

BiochemistryProtein AssemblyProtein FoldingNatural SciencesMedicine +5

CD70 as an actionable immunotherapeutic target in recurrent glioblastoma and its microenvironment

Mathieu Seyfrid, William Maich, Muhammad Vaseem Shaikh, +22

Journal for ImmunoTherapy of Cancer

Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma

Maleeha Qazi, Parvez Vora, Chitra Venugopal, +19

Cancer Research

A CD133-AKT-Wnt signaling axis drives glioblastoma brain tumor-initiating cells

Branavan Manoranjan, Chirayu Chokshi, Chitra Venugopal, +8

Oncogene

Neuro-oncologyBrain Tumor-initiating CellsMedicineCell BiologyCancer Biology +2

Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells

Chirayu Chokshi, Muhammad Vaseem Shaikh, Benjamin Brakel, +40

Nature Medicine

Neuro-oncologyAxonal Guidance DependenciesGliomaImmune Checkpoint InhibitorHigh-grade Gliomas +5

A phylogenomic and molecular markers based analysis of the phylum Chlamydiae: proposal to divide the class Chlamydiia into two orders, Chlamydiales and Parachlamydiales ord. nov., and emended description of the class Chlamydiia

Radhey S. Gupta, Sohail Naushad, Chirayu Chokshi, +2

Antonie van Leeuwenhoek

BiologyMicrobial SystematicsPhylogeneticsMolecular MarkersNatural Sciences +11

The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers

Nazanin Tatari, Shahbaz Khan, Julie Livingstone, +24

Acta Neuropathologica

Neuro-oncologyGliomaTumor HeterogeneityProteomic LandscapeMedicine +10

Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma

Maleeha Qazi, Sabra K. Salim, Kevin R. Brown, +24

Cell Reports

Evolutionary TrajectoriesPathologyHigh-grade GliomasCancer BiologyGlioma +14