Leonard H. van den Berg

Aging effects on DNA methylation modules in human brain and blood tissue

Steve Horvath, Yafeng Zhang, Peter Langfelder et al. · Genome biology · 2012 · 666 citations · Full text

Microglia innately develop within cerebral organoids

Paul R. Ormel, Renata Vieira de Sá, Emma J. van Bodegraven et al. · Nature Communications · 2018 · 600 citations · Full text

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis

Chi-Hong Wu, Claudia Fallini, Nicola Ticozzi et al. · Nature · 2012 · 594 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Developmental Biology +8

Disease variants alter transcription factor levels and methylation of their binding sites

Marc Jan Bonder, René Luijk, Daria V. Zhernakova et al. · Nature Genetics · 2016 · 544 citations · Full text

Epigenetic Change, Genetics, Dna Methylation +9

Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model

Henk-Jan Westeneng, Thomas P. A. Debray, Anne E Visser et al. · The Lancet Neurology · 2018 · 492 citations · Full text

Prognostic Assessment, Neurodegenerative Diseases, Personalised Prediction Model +12