Robert Manning

MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia

Steven P. Treon, Lian Xu, Guang Yang et al. · New England Journal of Medicine · 2012 · 1.3K citations · Full text

Medicine, Hematology, Molecular Genetics +15

The genomic landscape of Waldenström macroglobulinemia is characterized by highly recurring MYD88 and WHIM-like CXCR4 mutations, and small somatic deletions associated with B-cell lymphomagenesis

Zachary R. Hunter, Lian Xu, Guang Yang et al. · Blood · 2013 · 480 citations

Life Sciences, Genetics, Molecular Genetics +15

MYD88 L265P in Waldenström macroglobulinemia, immunoglobulin M monoclonal gammopathy, and other B-cell lymphoproliferative disorders using conventional and quantitative allele-specific polymerase chain reaction

Lian Xu, Zachary R. Hunter, Guang Yang et al. · Blood · 2013 · 413 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

A mutation in MYD88 (L265P) supports the survival of lymphoplasmacytic cells by activation of Bruton tyrosine kinase in Waldenström macroglobulinemia

Guang Yang, Yangsheng Zhou, Xia Liu et al. · Blood · 2013 · 347 citations

Life Sciences, Genetics, Molecular Biology +6

Increased natural killer cell expression of CD16, augmented binding and ADCC activity to rituximab among individuals expressing the FcγRIIIa-158 V/V and V/F polymorphism

Evdoxia Hatjiharissi, Lian Xu, Daniel Santos et al. · Blood · 2007 · 266 citations · Full text

Life Sciences, Cell Biology, Immunology +17