Helen Y. Figueroa

Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons

Jessica Wu, Mathieu Herman, Li Liu et al. · Journal of Biological Chemistry · 2012 · 536 citations · Full text

Pathology, Cell Death, Cellular Physiology +22

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease

Hongjun Fu, G Rodriguez, Mathieu Herman et al. · Neuron · 2017 · 291 citations · Full text

Neurodegenerative Diseases, Neurobiology Of Disease, Alzheimer's Disease +12

A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology

Hongjun Fu, Andrea Possenti, Rosie Freer et al. · Nature Neuroscience · 2018 · 258 citations · Full text

Neurodegenerative Diseases, Signal Transduction, Regional Vulnerability +9

Transcriptional Regulation of β-Secretase by p25/cdk5 Leads to Enhanced Amyloidogenic Processing

Wen Yi, Wai Haung Yu, Bryan Maloney et al. · Neuron · 2008 · 199 citations · Full text

Transcriptional Regulation, Signal Transduction, Enhanced Amyloidogenic Processing +7

Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathology

Tal Nuriel, Sergio Angulo, Usman Khan et al. · Nature Communications · 2017 · 191 citations · Full text