Adipose Tissue Macrophages Promote Myelopoiesis and Monocytosis in Obesity

Prabhakara R. Nagareddy, Michael J. Kraakman, Seth L. Masters, +15

Cell Metabolism

InflammationMetabolic SyndromeObesityBody CompositionAdipose Tissue +6

Neutrophil-Derived S100A8/A9 Amplify Granulopoiesis After Myocardial Infarction

Gopalkrishna Sreejit, Ahmed Abdel‐Latif, Baskaran Athmanathan, +17

Circulation

Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes

Michael J. Kraakman, Man K.S. Lee, Annas Al‐Sharea, +18

Journal of Clinical Investigation

Vascular DiseaseImmunologyPathologyCardiovascular Disease RiskInflammation +20

IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome

Andrew Murphy, Michael J. Kraakman, Hélène L. Kammoun, +18

Cell Metabolism

ObesityMetabolic SyndromeInflammationAnti-inflammatoryInflammatory Disease +8

Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis

Michelle Flynn, Michael J. Kraakman, Christos Tikellis, +23

Circulation Research

Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells

Nigora Mukhamedova, Anh Hoang, Dragana Dragoljevic, +13

PLoS Pathogens

ImmunologyImmune RegulationExtracellular MicrovesiclesInnate ImmunityImmune System +22

Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis

Dragana Dragoljevic, Michael J. Kraakman, Prabhakara R. Nagareddy, +14

European Heart Journal

High‐density lipoprotein inhibits human M1 macrophage polarization through redistribution of caveolin‐1

Man K.S. Lee, Xiao‐Lei Moore, Yi Fu, +7

British Journal of Pharmacology

Compound 21, a selective agonist of angiotensin AT₂ receptors, prevents endothelial inflammation and leukocyte adhesion <i>in vitro</i> and <i>in vivo</i>

Amanda K. Sampson, Jennifer C. Irvine, Waled Shihata, +9

British Journal of Pharmacology

Type I interferon antagonism of the JMJD3-IRF4 pathway modulates macrophage activation and polarization

Ming-Chin Lee, Adrian Achuthan, David P. De Souza, +11

Cell Reports

Macrophage ActivationInnate Immune SystemImmunologyImmune RegulationImmunologic Mechanism +18