Kailash Krishnan

Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial

Nikola Sprigg, Katie Flaherty, Jason P. Appleton et al. · The Lancet · 2018 · 481 citations · Full text

Medicine, Pharmacotherapy, Clinical Pharmacology +16

Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial

Rustam Al‐Shahi Salman, M. J. S. Dennis, PAG Sandercock et al. · The Lancet · 2019 · 195 citations · Full text

Medicine, Hematology, Pharmacotherapy +17

Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial

Philip M. Bath, Polly Scutt, Jason P. Appleton et al. · The Lancet · 2019 · 194 citations · Full text

Medicine, Neurology, Pharmacotherapy +17

Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial

Philip M. Bath, Lisa J Woodhouse, Jason P. Appleton et al. · The Lancet · 2017 · 180 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial

Isla S. Mackenzie, Christopher J. Hawkey, Ian Ford et al. · The Lancet · 2022 · 157 citations · Full text

Pharmacy, Cardiology, Pharmacotherapy +16