Individualized Systems Medicine Strategy to Tailor Treatments for Patients with Chemorefractory Acute Myeloid Leukemia

Tea Pemovska, Mika Kontro, Bhagwan Yadav, +33

Cancer Discovery

Methods for High-throughput Drug Combination Screening and Synergy Scoring

Liye He, Evgeny Kulesskiy, Jani Saarela, +4

Methods in molecular biology

Hit IdentificationSynergy ScoringMedicineRational Drug DesignPharmacology +2

Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia

Disha Malani, Ashwini Kumar, Oscar Brück, +24

Cancer Discovery

Automated Panning and Screening Procedure on Microplates for Antibody Generation from Phage Display Libraries

Laura Turunen, Kristiina Takkinen, Hans Söderlund, +1

SLAS DISCOVERY

Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins

Daria Bulanova, Aleksandr Ianevski, Yevhen Akimov, +39

Viruses

ImmunologyCell DeathAntiviral DrugImmunotherapyAntiviral Properties +14

Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM

Heike Peterziel, Nora Jamaladdin, Dina ElHarouni, +42

npj Precision Oncology

Patient-tailored design for selective co-inhibition of leukemic cell subpopulations

Aleksandr Ianevski, Jenni Lahtela, Komal Kumar Javarappa, +14

Science Advances

Precision Cancer Medicine in the Acoustic Dispensing Era: Ex Vivo Primary Cell Drug Sensitivity Testing

Evgeny Kulesskiy, Jani Saarela, Laura Turunen, +1

SLAS TECHNOLOGY

Biomedical AcousticsEngineeringBiological Effects Of Acoustic WavesAcoustic SensorTumor Biology +24

Human Tumor–Derived Matrix Improves the Predictability of Head and Neck Cancer Drug Testing

Katja Tuomainen, Ahmed Al‐Samadi, Swapnil Potdar, +11

Cancers

Systematic Mapping of Kinase Addiction Combinations in Breast Cancer Cells by Integrating Drug Sensitivity and Selectivity Profiles

Agnieszka Szwajda, Prson Gautam, Leena Karhinen, +8

Chemistry & Biology

Breast OncologyOncologySystematic MappingDrug TargetMedicine +9