S. Whitney Barnes

SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis

Kapil Tahlan, Regina Wilson, David B. Kastrinsky et al. · Antimicrobial Agents and Chemotherapy · 2012 · 498 citations · Full text

Membrane Transporter, Bioorganic Chemistry, Engineering +23

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

Shilpi Khare, A. S. Nagle, Agnes Biggart et al. · Nature · 2016 · 407 citations · Full text

Proteasome Inhibition, Medicinal Chemistry, Antiparasitic Agent +11

Imaging of <i>Plasmodium</i> Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

Stephan Meister, David Plouffe, Kelli Kuhen et al. · Science · 2011 · 347 citations · Full text

Antiparasitic Agent, Malaria, Pathology +16

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

Kévin Pethe, Patrícia Carvalho de Sequeira, Sanjay Agarwalla et al. · Nature Communications · 2010 · 303 citations · Full text

Bioorganic Chemistry, Tuberculosis Prevention, Bacteriology +24

Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse

Tim Wiltshire, Mathew T. Pletcher, Serge Batalov et al. · Proceedings of the National Academy of Sciences · 2003 · 229 citations · Full text

Biology, Disease Susceptibility, Phenotypic Variation +15